What is Candesartan?
The active ingredient Candesartan is one of the most prescribed hypertension drugs. It belongs to the group of sartans or angiotensin receptor antagonists (ARB). Sartans are receptor antagonists of the ACE receptors and, in addition to the ACE inhibitors and beta-blockers, are the most important drugs for lowering blood pressure. They block the docking site or the receptor of the hormone angiotensin II, suppressing its action. Normally, this hormone causes a rise in blood pressure because it provokes vasoconstriction, decreased kidney circulation, as well as increased recovery of sodium ions and water in the kidneys. Sartans have relatively few side effects as they interfere with the hormone control loop later than the ACE inhibitors.
What is Candesartan used for?
Candesartan can be prescribed for the treatment of:
- Cardiac insufficiency or heart failure, when ACE inhibitors are not tolerated or aren’t sufficiently effective as a single medication
What is Hypertension?
The natural regulation of blood pressure is a regular body function. When more energy is needed, the body automatically increases blood pressure and lowers it during the periods of rest. A disturbance in this natural system can lead to high blood pressure. Unfortunately, when this occurs, the patient does not feel it, as there are no clear symptoms. Consequently, the patient does not notice when hypertension gradually gets worse. Prolonged unnoticed hypertension can affect small vessels more, as they can be found in the eye and kidney. Long-term unrecognized hypertension may result in loss of vision and severe kidney dysfunction. In order to prevent consequential damage, you could exercise more, adopt a healthy diet, and take antihypertensive medication.
What is the effect of Candesartan?
This drug is a sartan and is involved in the so-called renin-angiotensin-aldosterone system of the human body, which regulates the electrolyte and fluid balance. It is also responsible for the regulation of blood pressure.
As a relatively new drug, it has very good tolerability. Candesartan is an angiotensin II receptor antagonist and inhibits the formation of vasoconstrictor messengers, such as angiotensin II. Also, it enhances the formation of vasodilators, such as Bradykinin. When using this treatment, your blood pressure is regulated and the heart is relieved.
In general, the therapy should begin with a low dosage of 4-8 mg. Depending on the doctor's instructions; the dose might be increased within a few weeks until the blood pressure is adequately regulated.
The tablets should be taken once a day. Besides, Candesartan can be supplemented with other blood pressure regulating medications, such as the dehydrating agent hydrochlorothiazide called HCT.
As with all medications, you may experience certain side effects when using this drug, especially at the beginning of the treatment.
Common side effects include:
- Circulatory problems
Less common side effects include:
- Gastrointestinal discomfort
- Heart stumbling
Besides, your potassium levels may increase during treatment. If any of the above or other side effects occur, tell your doctor immediately. Read the Patient Information Leaflet for detailed information on side effects, contraindications, and drug interactions.
Contraindications and interactions
Because it contains active ingredients, Candesartan can interact with other drugs. Moreover, it isn’t safe to take if you suffer from other health conditions.
Candesartan increases the effect of:
- Remedies for depression, like Amitriptyline or Imipramine
The following remedies reduce the effect of Candesartan:
- Painkillers such as Acetylsalicylic acid and Ibuprofen
Also, keep in mind:
- If the renal function is impaired, take a lower dose due to the slow elimination
- In impaired liver function, the conversion to the effective form takes longer and the effect occurs later
- Pregnant women in the second and third trimesters of pregnancy are not allowed to take Candesartan
Effective antihypertensive drugs at Apomeds
We understand that when prescribing this medicine, it should be checked beforehand if the patient is suitable for the blood pressure medication. Apomeds connects you to certified online pharmacies and EU-accredited physicians who check your completed questionnaire for contraindications and interactions with other medicines.
Please note that at Apomeds, antihypertensive drugs are only prescribed via follow-up prescription!
Other Hypertension medications you can find on our platform are:
All you need to do is choose the treatment and fill out an online questionnaire that will be reviewed by the EU-licensed doctors we work with. If you are eligible for the requested high blood pressure medication, the follow-up prescription will be issued and sent directly to your home, together with the remedy, in a discrete package.
Disclaimer: Please note that the drug you see in the picture indicates one of the possible manufacturers of the drug. We might send you a drug from a different manufacturer. All products comply with the highest EU standards.